To date basic visualization of sequence alignments have largely focused on displaying per-site columns of nucleotide, or amino acid, residues along with associated frequency summarizations.The persistence of this tendency to the recent tools designed for viewing mapped read data indicates that such a perspective not only provides a reliable visuali
TF-EPI: an interpretable enhancer-promoter interaction detection method based on Transformer
The detection of enhancer-promoter interactions (EPIs) is crucial for understanding gene expression regulation, disease mechanisms, and more.In this study, we developed TF-EPI, a deep learning model based on Transformer designed to Shopping Totes detect these interactions solely from DNA sequences.The performance of TF-EPI surpassed that of other s
(S)-4,5-Diphenyl-1-[1-phenyl-3-(phenylsulfanyl)propan-2-yl]-2-(thiophen-2-yl)-1H-imidazole
In the title compound, C34H28N2S2, the central imidazole ring (r.m.s.deviation = Quilts 0.0015 Å) forms dihedral angles of 55.7 (3), 17.94 (11) and 86.27 (11)°, respectively, with the mean planes of the attached thienyl and two phenyl substituents.The thienyl ring shows ring-flip disorder [occupancy ratio = 0.647&#